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Title Multiple sclerosis : immunology, pathology, and pathophysiology / Robert M. Herndon, editor
Published New York, N.Y. : Demos Medical Pub., [2003]
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Description 1 online resource (xii, 239 pages) : illustrations
Contents Developments in multiple sclerosis research / Robert M. Herndon -- Morphology of oligodendrocytes and myelin / Robert Skoff -- Astroctes: morphology and function / Robert M. Herndon -- Molecular structure of the myelin membrane / Joyce A. Benjamins -- The nature of immunologic privilege in the central nervous system / Zsuzsa Fabry, Matyas Sandor, Diane Sewell, and Emily Reinke -- Experimental autoimmune encephalomyelitis / LaChelle R. Arredondo, Amy Lovett-Racke, and Michael K. Racke -- Tissue culture studies of demyelination and remyelination / Frederick J. Seil -- Infectious agents and demyelination / John Rose -- Viral demyelinating diseases in experimental animals / Jane E. Libbey and Robert S. Fujinami -- Chlamydia pneumoniae infection and its association with multiple sclerosis / Harold Moses Jr. and Sabramaniam Sriram -- The role of cytokines in multiple sclerosis and experimental allergic encephalomyelitis / Tanuja Chitnis and Samia J. Khoury -- Chemokines and their receptors in multiple sclerosis / Richard M. Ransohoff and William J. Karpus -- Interferons in multiple sclerosis / Suhayl Dhib-Jalbut -- The pathology of multiple sclerosis as revealed by in vivo magnetic resonance-based approaches / Jack H. Simon -- Mechanisms of repair, adaptation, and recovery of function in multiple sclerosis / Robert M. Herndon
Summary Annotation From historical cases suggestive of multiple sclerosis and the 1838 clinical description of MS to the latest research, Dr. Herndon (neurology, U. of Mississippi Medical Center, Jackson) provides an overview of developments relating to this central nervous system autoimmune disease. In this companion volume to </Multiple sclerosis: diagnosis, medical management, and rehabilitation/> (Demos, 2000), US contributors to 16 chapters offer an overview of advances in the basic sciences and technologies as they pertain to understanding immune responses in MS (e.g., an animal model of demyelinating disease, identification of contributory infectious agents). The final chapter offers hope for remyelination of nerve fibers and recovery of function. Coverage of epidemiology and genetics is acknowledged as minimal. Annotation c. Book News, Inc., Portland, OR (
Annotation This volume provides an overview of MS-related research and will benefit many investigators in the field and help to advance our efforts to cure this, thus far, intractable disease
Notes Companion vol. to: Multiple sclerosis: diagnosis, medical management, and rehabilitation / edited by Jack S. Burks and Kenneth P. Johnson
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Multiple sclerosis.
Multiple Sclerosis -- immunology.
Multiple Sclerosis -- pathology.
Multiple Sclerosis -- physiopathology.
Form Electronic book
Author Herndon, Robert M.
ISBN 141755214X (electronic bk.)
1888799625 (paperback)
1934559261 (electronic bk.)
9781417552146 (electronic bk.)
9781888799620 (paperback)
9781934559260 (electronic bk.)
OTHER TI Multiple sclerosis