| Description |
1 online resource (xiii, 257 pages) : illustrations (some color) |
| Series |
Advances in experimental medicine and biology, 0065-2598 ; volume 887 |
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Advances in experimental medicine and biology ; v. 887.
|
| Contents |
A fleeting glimpse inside microRNA, epigenetics, and micropeptidomics -- Gaetano Santulli -- The microRNA Machinery -- Thomas C. Roberts -- MicroRNAs in mitochondria: an unexplored niche -- Pedro M. Borralho, Cecília M.P. Rodrigues, Clifford J. Steer -- MicroRNAs distinctively regulate vascular smooth muscle and endothelial cells: functional implications in angiogenesis, atherosclerosis, and in-stent restenosis -- Gaetano Santulli -- Mechanistic role of microRNAs in coupling lipid metabolism and atherosclerosis -- Jan Novák, Veronika Olejníčková, Nikola Tkáčová, Gaetano Santulli -- MicroRNAs in pancreatic [beta]-cell physiology -- Sabire Özcan -- microRNA and cardiac regeneration -- Massimiliano Gnecchi, Federica Pisano, Riccardo Bariani -- MicroRNAs and endometrial pathophysiology -- Henry H. Chill, Uri P. Dior, Liron Kogan, Ariel Revel -- microRNA and NF-kappa B -- Ye Yuan, Lingying Tong, Shiyong Wu -- MicroRNAs: key players in hematopoiesis -- Sanjeev Raghuwanshi [and others] -- Regulatory roles of miRNAs in aging -- Xurde M. Caravia, Carlos López-Otín -- Computational prediction of microRNA targets -- Alessandro Laganà |
| Summary |
This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. Chapters contributed by leading scientists examine recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness. The authors contextualize microRNAs within epigenetics and micropeptidomics, angiongenesis and atherosclerosis, endometrial pathophysiology, and more. Throughout, numerous color photographs, diagrams of molecular pathways, and tables enhance the text. microRNA: Basic Science is an ideal companion to both microRNA: Medical Evidence and microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice |
| Notes |
Includes index |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed December 21, 2015) |
| Subject |
Small interfering RNA.
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MicroRNA.
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MicroRNAs
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RNA, Small Interfering
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Nuclear physics.
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Zoology & animal sciences.
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Medical research.
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Physiology.
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Cellular biology (cytology)
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SCIENCE -- Life Sciences -- Biochemistry.
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MicroRNA
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Small interfering RNA
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| Form |
Electronic book
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| Author |
Santulli, Gaetano, editor.
|
| ISBN |
9783319223803 |
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3319223801 |
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