Description |
1 online resource (xi, 285 pages) : illustrations |
Series |
Biostatistics ; 13 |
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Biostatistics (New York, N.Y.) ; 13.
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Contents |
Part I. Methods for early trials -- 1. Bayesian Methods for Cancer Phase I Clinical Trials / James S. Babb and Andre Rogatko -- 2. Design of Early Trials in Stem Cell Transplantation : A Hybrid Frequentist-Bayesian Approach / Nancy L. Geller [and others] -- Part II. Methods for randomized trials -- 3. Design and Analysis of Therapeutic Equivalence Trials / Richard M. Simon -- 4. Adaptive Two-Stage Clinical Trials / Michael A. Proschan -- 5. Design and Analysis of Cluster Randomization Trials / David M. Zucker -- 6. Design and Analysis of Clinical Trials with Multiple Endpoints / Nancy L. Geller -- 7. Subgroups and Interactions / Dean Follmann -- 8. A Class of Permutation Tests for Some Two-Sample Survival Data Problems / Joanna H. Shih and Michael P. Fay -- 9. Bayesian Reporting of Clinical Trials / Simon Weeden, Laurence S. Freedman, and Mahesh Parmar -- Part III. More complex problems -- 10. Methods Incorporating Compliance in Treatment Evaluation / Juni Palmgren and Els Goetghebeur -- 11. Analysis of Longitudinal Data with Missingness / Paul S. Albert and Margaret C. Wu -- 12. Statistical Issues Emerging from Clinical Trials in HIV Infection / Abdel G. Babiker and Ann Sarah Walker |
Summary |
From aspects of early trials to complex modelling problems, this reference summarizes methodology used in the design and analysis of clinical trials. Chapters have been contributed by international methodologists experienced in clinical trials practice |
Bibliography |
Includes bibliographical references and index |
Notes |
Print version record |
Subject |
Clinical trials -- Statistical methods
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Biometry.
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Biometry -- methods
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Clinical Trials
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Biometry
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biometrics.
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MEDICAL -- Laboratory Medicine.
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Biometry
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Clinical trials -- Statistical methods
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Form |
Electronic book
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Author |
Geller, Nancy L., 1944-
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ISBN |
0824757076 |
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9780824757076 |
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9780203912881 |
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0203912888 |
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9781135524395 |
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1135524394 |
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9781135524340 |
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1135524343 |
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9781135524388 |
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1135524386 |
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9780824790325 |
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0824790324 |
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