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Title Cancer driver genes : methods and protocols / edited by Timothy K. Starr
Published New York, N.Y. : Humana Press : Springer, [2018]
©2019

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Description 1 online resource (xi, 214 pages) : illustrations (some color)
Series Methods in molecular biology, 1940-6029 ; 1907
Methods in molecular biology (Clifton, N.J.) ; v. 1907. 1064-3745
Contents Cancer gene discovery : past to present / Christopher R. Clark, Wilaiwan DuRose, and Timothy K. Starr -- Identification of cancer driver genes from a custom set of next generation sequencing data / Shu-Hsuan Liu and Wei-Chung Cheng -- Cancer gene discovery by network analysis of somatic mutations using the MUFFINN server / Heonjong Han, Ben Lehner, and Insuk Lee -- Identifying driver interfaces enriched for somatic missense mutations in tumors / Kivilcim Ozturk and Hannah Carter -- Identification of cancer genes based on de novo transposon insertion site analysis using RNA and DNA sequencing / Aaron Sarver -- Cell-based method for identification of chemotherapy resistance cancer genes / Raffaele Hellweg, Ashley Mooneyham, and Martina Bazzaro -- Engineering a bioartificial human colon model through decellularization and recellularization / Huanhuan Joyce Chen and Michael L. Shuler -- Mutagenesis screens for prostate cancer using replication-incompetent lentiviral vectors / Grant D. Trobridge -- Arrayed shRNA screening to identify suppressors of anchorage-independent growth / Ugur Eskiocak -- Genome-wide CRISPR/Cas9 screening for identification of cancer genes in cell lines / Charles H. Adelmann, Tim Wang, David M. Sabatini, and Eric S. Lander -- CRISPR/Cas9-based positive screens for cancer-related traits / Nicholas J. Slipek, Jyotika Varshney, and David A. Largaespada -- Ex vivo transposon-mediated genetic screens for cancer gene discovery / Kathryn A. O'Donnell, Yabin Guo, Shruthy Suresh, Barrett L. Updegraff, and Xiaorong Zhou -- Cancer gene discovery utilizing sleeping beauty transposon mutagenesis / Kelsie L. Becklin, Branden A. Smeester, and Branden S. Moriarity -- PiggyBac transposon-based insertional mutagenesis in mice / Mathias J. Friedrich, Iraad F. Bronner, Pentao Liu, Allan Bradley, and Roland Rad -- Liver-specific delivery of sleeping beauty transposon system by hydrodynamic injection for cancer gene validation / Amy P. Chiu and Vincent W. Keng -- Engineering large genomic rearrangement in mouse embryonic stem cell for cancer gene discovery / Yuen-Yi Tseng and Anindya Bagchi
Bibliography Includes bibliographical references and index
Subject Cancer -- Genetic aspects -- Laboratory manuals
Biological models.
Neoplasms -- therapy
Biomedical Research
Computational Biology
Models, Biological
Biological models
Cancer -- Genetic aspects
Genre/Form Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Starr, Timothy K., editor
ISBN 9781493989676
1493989677