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E-book

Title Networks in systems biology : applications for disease modeling / Fabricio Alves Barbosa da Silva, Nicolas Carels, Marcelo Trindade dos Santos, Francisco José Pereira Lopes, editors
Published Cham : Springer, 2020

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Description 1 online resource (x, 377 pages) : illustrations (some color)
Series Computational biology, 1568-2684 ; v. 32
Computational biology ; v. 32. 1568-2684
Contents 1. Network Medicine: Methods and Applications -- 2. Computational Tools to Compare Biological Networks -- 3. Functional Gene Networks and their Applications -- 4. A Review of Artificial Neural Networks for the Prediction of Essential Proteins -- 5. Transcriptograms: A Genome Wide Gene Expression Analysis Method -- 6. A Tutorial on Sobols' Global Sensitivity Analysis Applied to Biological Models -- 7. Reaction Network Models as a Tool to Study Gene Regulation and Cell Signaling in Development and Diseases -- 8. Challenges for the Optimization of Drug Therapy in the Treatment of Cancer -- 9. Opportunities and Challenges Provided by Boolean Modelling of Cancer Signalling Pathways -- 10. Integrating Omics Data to Prioritize Target Genes in Pathogenic Bacteria -- 11. Modelling Oxidative Stress Pathways -- 12. Computational Modeling in Virus Infections and Virtual Screening, Docking and Molecular Dynamics in Drug Design -- 13. Cellular Regulatory Network Modeling Applied to Breast Cancer
Summary This book presents a range of current research topics in biological network modeling, as well as its application in studies on human hosts, pathogens, and diseases. Systems biology is a rapidly expanding field that involves the study of biological systems through the mathematical modeling and analysis of large volumes of biological data. Gathering contributions from renowned experts in the field, some of the topics discussed in depth here include networks in systems biology, the computational modeling of multidrug-resistant bacteria, and systems biology of cancer. Given its scope, the book is intended for researchers, advanced students, and practitioners of systems biology. The chapters are research-oriented, and present some of the latest findings on their respective topics
Notes Includes index
Online resource; title from PDF title page (SpringerLink, viewed December 3, 2020)
Subject Systems biology.
Bioinformatics.
Computer simulation.
Medical informatics.
Cancer -- Research.
Systems Biology
Computational Biology
Computer Simulation
simulation.
Life sciences: general issues.
Computer modelling & simulation.
Medical equipment & techniques.
Oncology.
Science -- Life Sciences -- General.
Computers -- Computer Simulation.
Medical -- General.
Medical -- Oncology.
Computers -- Computer Science.
Bioinformatics
Cancer -- Research
Computer simulation
Medical informatics
Systems biology
Form Electronic book
Author Silva, Fabricio Alves Barbosa da, editor.
Carels, Nicolas, editor
Trindade dos Santos, Marcelo, editor
Lopes, Francisco José Pereira, editor
ISBN 9783030518622
3030518620