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Book Cover
E-book

Title Systems biology / Michael G. Katze, editor
Published Berlin : Springer, 2013

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Description 1 online resource (276 pages)
Series Current Topics in Microbiology and Immunology ; v. 363
Current topics in microbiology and immunology ; v. 363.
Contents Systems approaches to dissecting immunity / Alan Diercks, Alan Aderem -- Studying Salmonellae and Yersiniae host-pathogen interactions using integrated 'omic and modeling / Charles Ansong [and others] -- ChIP-Seq and the complexity of bacterial transcriptional regulation / James Galagan, Anna Lyubetskaya, Antonio Gomes -- The role and contributions of systems biology to the non-human primate model of influenza pathogenesis and vaccinology / Carole Baskin -- 'Omics investigations of HIV and SIV pathogenesis and innate immunity / Robert E. Palermo, Deborah H. Fuller -- Systems biology of vaccination in the elderly / Sai S. Duraisingham [and others] -- Systems biology analyses to define host responses to HCV infection and therapy / Renee C. Ireton, Michael Gale -- Systems biology approach for new target and biomarker identification / I-Ming Wang [and others] -- Insights into proteomic immune cell signaling and communication via data-driven modeling / Kelly F. Benedict, Douglas A. Lauffenburger -- Critical dynamics in host-pathogen systems / Arndt G. Benecke
Summary First, systems biology is an inter-disciplinary approach, requiring the combined talents of biologists, mathematicians, and computer scientists. Second, systems biology is holistic, with the goal of obtaining a comprehensive understanding of the workings of biological systems. This is achieved through the acquisition of massive amounts of data by high-throughput technologies-oligonucleotide microarrays, mass spectrometry, and next-generation sequencing-and the analysis of this data through sophisticated mathematical algorithms
Bibliography Includes bibliographical references
Notes English
Print version record
Subject Systems biology.
Computational biology.
Computational Biology
Systems Biology
NATURE -- Reference.
SCIENCE -- Life Sciences -- Biology.
SCIENCE -- Life Sciences -- General.
Computational biology
Systems biology
Form Electronic book
Author Katze, Michael G
ISBN 9783642330995
3642330991
3642330983
9783642330988
1283945967
9781283945967