| Description |
1 online resource (612 pages) : color illustrations |
| Series |
Frontiers in Parasitology ; volume 1 |
|
Frontiers in Parasitology ; v. 1
|
| Contents |
FOREWORD ; PREFACE ; List of Contributors ; The Cellular Organization of Trypanosomatids During Life Cycle ; INTRODUCTION; NUCLEUS; Nuclear Organization; Nuclear Pore Complex; Nuclear Lamin; Nucleolus; Chromatin; Histone Post-Translational Modifications (PTM) in Trypanosomes; Chromatin Regulation at Specific Genomic Regions; DNA Modifications; CYTOSKELETON; FLAGELLUM; MITOCHONDRION; Organization of Mitochondrial DNA; Protein Synthesis in the Mitochondrion; ENDOPLASMIC RETICULUM; GLYCOSOMES; MEMBRANE TRAFFICKING AND THE GOLGI COMPLEX; LYSOSOMES AND ACIDIC ORGANELLES; Reservosomes |
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AcidocalcisomesCONCLUDING REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; ABBREVIATIONS; REFERENCES; Trypanosomatid Genome Organization and Ploidy ; INTRODUCTION; EPIDEMIOLOGICAL CONTEXT OF THE TRYPANOSOMATIDS; Leishmania: The Causative Agent of Leishmaniasis; T. cruzi: The Causative Agent of Chagas Disease; T. brucei: The Causative Agent of Sleeping Sickness; LIFE CYCLE; The Life Cycle of Leishmania spp.; The Life Cycle of Trypanosoma cruzi ; The Life Cycle of Trypanosoma brucei ; TAXONOMY OF THE TRITRYPS; GENOME ORGANIZATION; Trypanosomatid Comparative Genomics; Leishmania Genomic Features |
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Trypanosoma GenusTrypanosoma brucei Sub-species Complex; T. cruzi and Close Related Parasites; CONCLUDING REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; ABBREVIATIONS; REFERENCES; Chromosomes Ends and Telomere Biology of Trypanosomatids ; INTRODUCTION; OVERALL STRUCTURE OF TELOMERES; THE STRUCTURE OF SUBTELOMERIC REGIONS; Size, Sequence Content and Organization of T. cruzi and T. rangeli Subtelomeres; Organization of Leishmania Subtelomeres; Telomeric DNA Modification, the Base J; FORMATION OF NEW TELOMERES IN T. CRUZI ; TELOMERE MAINTENANCE IN TRYPANOSOMATIDS; ARTIFICIAL CHROMOSOMES |
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CONCLUDING REMARKSCONFLICT OF INTEREST; ACKNOWLEDGEMENTS; ABBREVIATIONS; REFERENCES; Nuclear and Kinetoplast DNA Replication in Trypanosomatids ; INTRODUCTION; DNA POLYMERASES; Trypanosomatids DNA Polymerases; NUCLEAR DNA REPLICATION; Recognition of Origins and Assembly/Activation of Pre-replication Complex; Origins Recognition, Licensing and Firing in Trypanosomatids; Replication Fork Progress; Telomere Replication and Elongation; Control and Regulation of Nuclear DNA Replication; KINETOPLAST DNA REPLICATION; Components of kDNA: Mini- and Maxicircles |
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KDNA Replication: Mechanisms and Proteins InvolvedMechanisms of kDNA Replication; Proteins Involved in kDNA Replication; Control and Regulation of kDNA Replication; Redox Regulation of UMSBP Binding; Expression of mRNA; CONCLUDING REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; ABBREVIATIONS; REFERENCES; Genome Maintenance in Trypanosomatids ; INTRODUCTION; The Genomes of Kinetoplastids; NUCLEOTIDE EXCISION REPAIR: MECHANISTIC STREAMLINING AND NEOFUNCTIONALISATION; THE DUAL ROLE OF MISMATCH REPAIR IN DNA REPAIR AND IN THE OXIDATIVE STRESS RESPONSE; BASE EXCISION REPAIR |
| Notes |
HOMOLOGOUS RECOMBINATION: ADAPTATIONS FOR GENOME VARIATION? |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (EBSCO, viewed July 3, 2017) |
| Subject |
Trypanosomatidae.
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SCIENCE -- Life Sciences -- Zoology -- General.
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Trypanosomatidae
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| Form |
Electronic book
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| Author |
Silva, Marcelo Santos da
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|
Cano, Maria Isabel N
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| ISBN |
9781681084053 |
|
1681084058 |
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