| Description |
1 online resource |
| Series |
Molecular nutrition series |
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Molecular nutrition series.
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| Contents |
Front Cover; The Molecular Nutrition of Amino Acids and Proteins; Copyright Page; Contents; List of Contributors; Preface; I. General and Introductory Aspects; 1 Bioactive Peptides Derived From Food Proteins; 1.1 Physiological Effects of Food-Derived Peptides; 1.2 In Vivo Evidence of Food-Derived Peptide Effects; 1.3 Bioactive Peptides Released During Digestion; 1.4 Peptide Bioavailability; 1.5 Conclusion; References; 2 Protein Intake Throughout Life and Current Dietary Recommendations; 2.1 Introduction; 2.2 Current Estimates for Protein and Amino Acid Requirements Throughout Life |
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2.3 Theoretical and Practical Limitations and Uncertainties2.4 Evidence for Defining Requirements Based on Meals Rather Than an Average Daily Intake in Older People; 2.5 Toward Other Criteria to Define Requirements, Using Health-Related Parameters?; 2.6 Current Dietary Intake of Protein and Amino Acids; 2.7 Conclusion and Perspectives; References; 3 Cellular Mechanisms of Protein Degradation Among Tissues; 3.1 Introduction; 3.2 Proteolytic Systems; 3.2.1 Ca2+-Dependent Proteolysis; 3.2.2 Caspases; 3.2.3 The Ubiquitin-Proteasome System; 3.2.3.1 Ubiquitination; 3.2.3.2 Proteasome Degradation |
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3.2.4 Autophagy3.2.5 Metalloproteinases; 3.3 Skeletal Muscle Proteolysis; 3.3.1 UPS: The Main Player for Myofibrillar Protein Degradation; 3.3.1.1 Role of the E1 Enzyme; 3.3.1.2 Role of E2 Enzymes; 3.3.1.3 Role of E3 Enzymes; 3.3.1.4 Role of the Proteasome; 3.3.2 Autophagy-Lysosome System in Skeletal Muscle; 3.3.2.1 Role of Cathepsins; 3.3.2.2 Autophagy: A Crucial Pathway for Muscle Mass Maintenance; 3.3.3 Functional Cooperation of Proteolytic Systems for Myofibrillar Protein Degradation; 3.4 Proteolysis in Viscera; 3.4.1 Liver and Autophagy: For Regulation of Energy Metabolism |
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3.4.2 A Major Role of Autophagy in Small Intestine3.4.2.1 For Amino Acids Supply to Peripheral Tissues; 3.4.2.2 For Regulation of the Epithelial Barrier; 3.5 Concluding Remarks; Acknowledgments; References; 4 Cellular and Molecular Mechanisms of Protein Synthesis Among Tissues; 4.1 Introduction; 4.1.1 Molecular Basics of Protein Synthesis; 4.1.2 Introduction of the Intracellular Regulation of Protein Synthesis; 4.1.3 Endogenous and Exogenous Regulators of Protein Synthesis; 4.2 Cellular and Molecular Regulation of Hypertrophy; 4.3 Myogenesis: The Development and Regeneration of Muscle |
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4.4 Applied Implications of Protein Synthesis In Vivo4.5 Conclusions and Summary of Key Points; Disclosures; References; 5 Role of Amino Acid Transporters in Protein Metabolism; 5.1 Amino Acid Transporters: Structure and Molecular Function; 5.2 AA Transporters and Cellular Function; 5.2.1 Cellular Nutrient Supply; 5.2.2 Nutrient Sensing; 5.2.2.1 AA Transporters as AA Sensors; 5.2.2.2 AA Transporters Upstream of Intracellular AA Sensors; 5.2.3 Cell-Cell Communication; 5.3 AA Transporters in Whole-Body Nutrition; 5.3.1 Absorption of AA and Peptides; 5.3.2 Interorgan Nitrogen Flow |
| Notes |
Includes index |
| Bibliography |
Includes bibliographical references at the end of each chapters and index |
| Notes |
Online resource; title from PDF title page (ScienceDirect, viewed June 21, 2016) |
| Subject |
Amino acids in human nutrition.
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Proteins in human nutrition.
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Amino acids.
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Amino Acids
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HEALTH & FITNESS -- Healthy Living.
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HEALTH & FITNESS -- Holism.
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HEALTH & FITNESS -- Reference.
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MEDICAL -- Preventive Medicine.
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Amino acids
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Amino acids in human nutrition
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Proteins in human nutrition
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| Form |
Electronic book
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| Author |
Dardevet, Dominique, editor
|
| ISBN |
9780128023754 |
|
0128023759 |
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