| Description |
1 online resource (xv, 286 pages) : illustrations |
| Contents |
Structural analysis of toll-like receptors / by Jungwoo Choe and Ian A. Wilson -- Antiviral signaling through TLRs and RLHs / by Taro Kawai -- Recognition of virus invasion by toll-like receptors and RIG-I-like helicases / by Hiroki Kato and Osamu Takeuchi -- Characteristics of dendritic cell responses to nucleic acids / by Tsuneyasu Kaisho, Takahiro Sugiyama, and Katsuaki Hoshino -- Dendritic cells as sensors for foreign and self nucleic acids / by Anne Krug and Wolfgang Reindl -- Natural DNA recognition by toll-like receptor 9 does not reply upon CpG motifs: role of endosomal compartmentation / by Tobias Haas [and others] -- Discrimination of self and non-self DNA / by Katryn J. Stacey [and others] -- Therapeutic potential of immunosuppressive oligonucleotides expressing TTAGGG motifs / by Dennis M. Klinman [and others] -- Structure/function of IFN?-inducing CpG ODN / by Daniela Verthelyi and Montserrat Puig |
|
Clinical development of oligodeoxynucleotide TLR9 agonists / by Julie L. Himes and Arthur M. Krieg -- Prospects for TLR9- based immunotherapy for asthma and allergy / by David Broide -- Toll-like receptors in the development of systemic autoimmune disease : in vitro artifact or in vivo paradigm? / by Ann Rothstein -- Impacts of nucleoside modification on RNA-mediated activation of toll-like receptors / by Katalin Karikó and Drew Weissman -- Activation of innate pattern recognition pathways by single-stranded ribonucleic acids / by Sandra Diebold -- RNA interference in scope of immune system / by Andrea Ablasser, Gunther Hartmann, and Veit Hornung -- Recognition of RNA and synthetic compounds by TLR7 and TLR8 / by Svetlana Hamm and Stefan Bauer -- Helicases at frontline of RNA virus recognition / by Leonid Gitlin and Marco Colonna |
| Summary |
Offering insight into areas of immunology, this book explains the roles of nucleic acids in immunity, describing the mechanism of discrimination based on pattern-recognition receptors (PRRs). It discusses how these PRRs recognize and respond to pathogen-associated molecular patterns (PAMPs) by activating specific signaling pathways |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Natural immunity.
|
|
Nucleic acids.
|
|
Autoimmunity.
|
|
Immunity, Innate -- physiology
|
|
Immunity, Innate
|
|
Autoimmunity
|
|
DNA -- immunology
|
|
RNA -- immunology
|
|
Receptors, Pattern Recognition -- immunology
|
|
Self Tolerance
|
|
MEDICAL -- Immunology.
|
|
Autoimmunity
|
|
Natural immunity
|
|
Nucleic acids
|
|
Angeborene Immunität
|
|
Immunreaktion
|
|
Nucleinsäuren
|
| Genre/Form |
Electronic books
|
|
Aufsatzsammlung.
|
| Form |
Electronic book
|
| Author |
Ishii, Ken J
|
|
Akira, S
|
| ISBN |
9781420068269 |
|
1420068261 |
|
9780429149870 |
|
0429149875 |
|
