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E-book

Title Renal tumors of childhood : biology and therapy / Kathy Pritchard-Jones, Jeffrey S. Dome, editors
Published Heidelberg : Springer, 2014

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Description 1 online resource (x, 281 pages) : illustrations (some color)
Series Pediatric oncology, 2191-0812
Pediatric oncology (Series)
Contents 1. Epidemiology of renal tumors of childhood / Charles A. Stiller, Andrew F. Olshan -- 2. Genetic predisposition to Wilms tumor / Richard H. Scott, Nazneen Rahman -- 3. Clinical presentation / Elizabeth Mullen, Norbert Graf -- 4. Pathology of renal tumors of childhood / Gordan M. Vujanic -- 5. Treatment of Wilms tumor in the Children's Oncology Group / Conrad Fernandez -- 6. Treatment of Wilms tumor: the SIOP approach / Rhoikos Furtwängler, Kathy Pritchard-Jones -- 7. Treatment of relapsed Wilms tumor / Filippo Spreafico, Marcio H. Malogolowkin -- 8. Imaging / Geetika Khanna, Øystein E. Olsen -- 9. Biological prognostic factors in Wilms tumors / Kathy Pritchard-Jones, Mariana Maschietto, Paul Grundy -- 10. Molecular-targeted therapy for pediatric renal tumors / James I. Geller, Peter Hohenstein -- 11. Surgical consideration for Wilms' tumors and other neoplastic renal lesions / Peter F. Ehrlich, Jan Godzinski -- 12. Radiotherapy for Wilms' tumor and other childhood renal cancers / Mark N. Gaze, John A. Kalapurakal -- 13. Late effects and QOL chapter / Gill A. Levitt, Daniel M. Green -- 14. Non-Wilms pediatric renal tumors / JEffrey S. Dome, Saskia L. Gooskens, M.M. van den Heuvel-Eibrink -- 15. Wilms tumor in countries with limited resources / Monika Metzger, Judith A. Wilimas, Mhamed Harif, Trijn Israels
Summary This book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratification and to incorporate biologically targeted agents into front-line therapy are discussed. In addition, the current state of thinking of the two major clinical trial groups in these diseases is presented. All of the authors are experts from Europe and North America, and the book has been written specifically as an easy reference for the practising clinician and the research scientist. It lays the basis for understanding the future direction of clinical and translational research to improve outcomes in patients with childhood renal tumors and will prove indispensable for those treating or researching into these diseases
Analysis pathologie
pathology
oncologie
oncology
chirurgie
surgery
pediatrie
paediatrics
geneeskunde
medicine
volksgezondheid
public health
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references
Notes English
Online resource; title from PDF title page (SpringerLink, viewed February 11, 2015)
Subject Kidneys -- Cancer.
Tumors in children.
Pediatric nephrology.
Children.
Kidney Neoplasms
Child
children (people by age group)
MEDICAL -- Pediatrics.
MEDICAL -- Nephrology.
MEDICAL -- Oncology.
Children
Kidneys -- Cancer
Pediatric nephrology
Tumors in children
Form Electronic book
Author Pritchard-Jones, Kathy, editor.
Dome, Jeffrey S., editor.
ISBN 9783662440032
3662440032
3662440024
9783662440025