| Description |
1 online resource (xii, 590 pages) : illustrations (some color) |
| Series |
AAPS advances in the pharmaceutical sciences series, 2210-7371 ; 2 |
|
AAPS advances in the pharmaceutical sciences series ; v. 2. 2210-7371
|
| Contents |
Selection of drug delivery approaches for the back of the eye: opportunities and unmet needs / David A. Marsh -- Microdialysis for vitreal pharmacokinetics / Ravi D. Vaishya, Hari Krishna Ananthula, and Ashim K. Mitra -- Fluorophotometry for pharmacokinetic assessment / Bernard E. McCarey -- Systemic route for retinal drug delivery: role of the blood-retinal barrier / Masanori Tachikawa, Vadivel Ganapathy, and Ken-ichi Hosoya -- Topical drug delivery to the back of the eye / Thomas Gadek and Dennis Lee -- Principles of retinal drug delivery from within the vitreous / Clive G. Wilson, Lay Ean Tan, and Jenifer Mains -- Transscleral drug delivery / Dayle H. Geroski and Henry F. Edelhauser -- Suprachoroidal and intrascleral drug delivery / Timothy W. Olsen and Brian C. Gilger -- Advances in biodegradable ocular drug delivery systems / Susan S. Lee, Patrick Hughes, Aron D. Ross, and Michael R. Robinson -- Microparticles as drug delivery systems for the back of the eye / Rocio Herrero-Vanrell -- Nanotechnology and nanoparticles / Shelley A. Durazo and Uday B. Kompella -- Hydrogels for ocular posterior segment drug delivery / Gauri P. Misra, Thomas W. Gardner, and Tao L. Lowe -- Refillable devices for therapy of ophthalmic diseases / Alan L. Weiner -- Targeted drug delivery to the eye enabled by microneedles / Samirkumar R. Patel, Henry F. Edelhauser, and Mark R. Prausnitz -- Ocular iontophoresis / Francine F. Behar-Cohen, Peter Milne, Jean-Marie Parel, and Indu Persaud -- Drug and gene therapy mediated by physical methods / John M. Nickerson and Jeffrey H. Boatright -- Protein drug delivery and formulation development / Rinku Baid, Puneet Tyagi, Shelley A. Durazo, and Uday B. Kompella -- Drug suspension development for the back of the eye / Jithan Aukunuru, Puneet Tyagi, Chandrasekar Durairaj, and Uday B. Kompella -- Regulatory considerations in product development for the back of the eye / Ashutosh A. Kulkarni -- Clinical endpoints for back of the eye diseases / Karl G. Csaky -- Druggable targets and therapeutic agents for disorders of the back of the eye / Robert I. Scheinman, Sunil K. Vooturi, and Uday B. Kompella -- Development of bile acids as anti-apoptotic and neuroprotective agents in treatment of ocular disease / Stephanie L. Foster, Cristina Kendall, Allia K. Lindsay, Alison C. Ziesel, Rachael S. Allen, Sheree S. Mosley, Esther S. Kim, Ross J. Molinaro, Henry F. Edelhauser, Machelle T. Pardue, John M. Nickerson, and Jeffrey H. Boatright |
| Summary |
This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms; Refillable and microneedle devices; Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery; Physical methods including iontophoresis for drug delivery; Rational selection of routes of administration and delivery systems; Noninvasive |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Ocular pharmacology.
|
|
Ophthalmology.
|
|
Drugs -- Dosage forms.
|
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Drugs -- Administration.
|
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Drug Delivery Systems -- methods
|
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Eye Diseases -- drug therapy
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Dosage Forms
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Drug Administration Routes
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Ophthalmology
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Drugs -- Dosage forms
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Drugs -- Administration
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Ocular pharmacology
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Ophthalmology
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| Form |
Electronic book
|
| Author |
Kompella, Uday B
|
|
Edelhauser, Henry F
|
|
American Association of Pharmaceutical Scientists.
|
| ISBN |
9781441999207 |
|
1441999205 |
|
