Cover; Half-title; Title; Copyright; Contents; Contributors; Foreword; Preface; RECOMBINANT ANTIBODIES FOR IMMUNOTHERAPY; PART I HUMANIZED ANTIBODIES; CHAPTER ONE Humanization of Recombinant Antibodies; CHAPTER TWO Immunogenicity Assessment of Antibody Therapeutics; CHAPTER THREE In Vitro Screening for Antibody Immunogenicity; PART II GENERATION AND SCREENING OF ANTIBODY LIBRARIES; CHAPTER FOUR Antibody Libraries from Naive V Gene Sources; CHAPTER FIVE Antibodies from IgM Libraries; CHAPTER SIX Generation and Screening of the Synthetic Human Combinatorial Antibody Library HuCAL GOLD
PART III TRANSGENIC HUMAN ANTIBODY REPERTOIRESCHAPTER SEVEN Therapeutic Antibodies from XenoMouse Transgenic Mice; CHAPTER EIGHT VelocImmune: Immunoglobulin Variable Region Humanized Mice; PART IV ANTIBODY EFFECTOR FUNCTION; CHAPTER NINE Mechanisms of Tumor Cell Killing by Therapeutic Antibodies; CHAPTER TEN Optimization of Fc Domains to Enhance Antibody Therapeutics; CHAPTER ELEVEN Glycoengineered Therapeutic Antibodies; PART
Summary
This book provides a comprehensive overview of the field of monoclonal antibodies through twenty-five articles by recognized experts in the field
