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E-book

Title Smart materials for tissue engineering : fundamental principles / editor: Qun Wang
Published [Cambridge] : Royal Society of Chemistry, [2017]

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Description 1 online resource
Series Smart materials series ; 24
RSC smart materials ; 24
Contents Cover; Smart Materials for Tissue Engineering: Fundamental Principles; Foreword; Preface; Contents; Chapter 1 -- Smart Design of Materials for Tissue Engineering; 1.1 Introduction; 1.2 Mechanism Underlying Interaction of Cells with the Extracellular Matrix; 1.2.1 Direct Physical Signal Transmission Pathway; 1.2.2 Indirect Mechanochemical Signal Transduction Pathway; 1.2.3 Control of Cell Differentiation, Proliferation, and Migration by Defining the Dynamics of the Cell Adhesion Complex and Act ... ; 1.2.3.1 Stem Cell Differentiation; 1.2.3.2 Cell Proliferation; 1.2.3.3 Cell Migration
1.3 Determinants of Cell Fate in the Extracellular Matrix1.3.1 Composition of Cell Adhesion Proteins; 1.3.2 ECM Topography; 1.3.3 ECM Stiffness; 1.4 Spatial and Temporal Scales in Cell and Material Interactions; 1.4.1 Molecular Level: Integrin; 1.4.2 Molecular Assembly Level; 1.4.2.1 Integrin Cluster; 1.4.2.2 Actin Cytoskeleton; 1.4.3 Single-Cell Level; 1.4.4 Multiple-Cell Level; 1.4.5 Integration of Multiple Spatiotemporal Effects; 1.5 Smart Design of Materials to Control the Dynamic State of Tissues; 1.6 Future Challenges; Acknowledgements; References
Chapter 2 -- Smart Surfaces Chemistry and Coating Materials for Tissue Engineering2.1 Introduction; 2.1.1 Tissue Engineering and Scaffolds; 2.1.2 Cell-EMC Interaction via Integrin and Surface Topography; 2.2 RGD Nanospacing; 2.2.1 Nanospacing in 2-D Substrates with Different Stiffness; 2.2.2 3-D Substrates; 2.3 Surface Topography-Mediated Stem Cell Fate; 2.4 Scaffold-Mediated Gene Delivery by Biomimetic Coating; 2.4.1 Gene-Transfer; 2.4.2 DNA/CP Complex as a Drug-Delivery System by Biomimetic Coating; 2.4.3 Polyplexes as Drug-Delivery Systems; 2.4.4 Targeting the Nucleus
2.4.5 Multi-Modal Delivery2.4.6 Scaffolds for Bone Tumor Destruction; 2.5 Concluding Remarks and Perspectives; References; Chapter 3 -- Protein-Based Stimuli Responsive Materials for Tissue Engineering; 3.1 Stimuli Responsiveness; 3.2 Types of Stimuli Responsiveness; 3.2.1 Temperature Responsiveness; 3.2.2 Electrical Responsiveness; 3.2.3 Light Responsiveness; 3.2.4 pH Responsive; 3.2.5 Redox Responsiveness; 3.2.6 Ion-Responsive Polymers; 3.2.7 Glucose Responsiveness; 3.2.8 Enzyme-Responsive Polymers; 3.3 Types of Polymeric Stimuli-Responsive Structures; 3.3.1 Hydrogels; 3.3.2 Micelles
3.3.3 Dendrimers3.3.4 Nanoparticles; 3.4 Protein-Based Responsive Systems; 3.5 Application in Tissue Engineering; 3.6 Conclusions and Future Perspectives; Acknowledgements; References; Chapter 4 -- Stimuli-Responsive Hydrogels for Tissue Engineering; 4.1 Introduction; 4.2 The Properties of Hydrogels for Tissue Engineering; 4.2.1 Mechanical Properties of Hydrogels; 4.2.2 Surface Chemistry of Hydrogels; 4.2.3 Biocompatibility and Biodegradability of Hydrogels; 4.2.4 Electrical Properties of Hydrogels; 4.3 Stimuli-Responsive Hydrogels; 4.3.1 Natural-Based Smart Hydrogels; 4.3.1.1 Chitosan
Summary This book focusses on the fundamental principles and recent advances in the materials science developed for tissue engineering purposes
Subject Biomedical materials.
Smart materials.
Tissue engineering.
Tissue Engineering
Biocompatible Materials
Biomedical and Dental Materials
HEALTH & FITNESS -- Holism.
HEALTH & FITNESS -- Reference.
MEDICAL -- Alternative Medicine.
MEDICAL -- Atlases.
MEDICAL -- Essays.
MEDICAL -- Family & General Practice.
MEDICAL -- Holistic Medicine.
MEDICAL -- Osteopathy.
Biomedical materials.
Smart materials.
Tissue engineering.
Form Electronic book
Author Wang, Qun
ISBN 9781782626756
1782626751