| Description |
x, 277 pages : illustrations (some color) ; 27 cm |
| Series |
Methods in molecular biology, 1064-3745 ; 670 |
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Springer protocols |
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Methods in molecular biology (Clifton, N.J.) ; v. 670. 1064-3745
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Springer protocols (Series)
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| Contents |
Contemporary approaches to Alzheimer's disease and frontotemporal dementia / Erik D. Roberson -- Preparing synthetic A[beta] in different aggregation states / W. Blaine Stine ... [et al.] -- Isolation of low-n amyloid [beta]-protein oligomers from cultured cells, CSF, and brain / Ganesh M. Shankar ... [et al.] -- Detecting A[beta]*56 oligomers in brain tissues / Mathew A. Sherman and Sylvain E. Lesné -- Assessing A[beta] aggregation state by atomic force microscopy / Justin Legleiter -- Measuring APP carboxy-terminal fragments / Luke A. Esposito -- Detection of APP intracellular domain in brain tissue / Sanjay W. Pimplikar and Anupama Suryanarayana -- Cell-based assays for regulators of tau biology / Umesh K. Jinwal and Chad A. Dickey -- Split GFP complementation assay for quantitative measurement of tau aggregation in situ / Wanjoo Chun, Geoffrey S. Waldo, and Gail V.W. Johnson -- Apolipoprotein E expression and purification / Yvonne Newhouse and Karl H. Weisgraber -- A[beta] toxicity in primary cultured neurons / Adriana Ferreira ... [et al.] -- Manipulation of gene expression in the central nervous system with lentiviral vectors / Binggui Sun and Li Gan -- Selecting a mouse model of Alzheimer's disease / Jeannie Chin -- Monitoring spatial learning and memory in Alzheimer's disease mouse models using the Morris water maze / Kimberly Scearce-Levie -- Step-by-step in situ hybridization method for localizing gene expression changes in the brain / Jorge J. Palop, Erik D. Roberson, and Inma Cobos -- Real-time visualization of axonal transport in neurons / Yasuko Osakada and Bianxiao Cui -- Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease : depletion of calcium-dependent proteins and inhibitory hippocampal remodeling / Jorge J. Palop, Lennart Mucke, and Erik D. Roberson -- Epigenetic changes in the brain : measuring global histone modifications / Gavin Rumbaugh and Courtney A. Miller |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Dementia.
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Alzheimer's disease.
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Alzheimer Disease.
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Frontotemporal Dementia.
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Models, Neurological.
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| Author |
Roberson, Erik D.
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| LC no. |
2010938365 |
| ISBN |
9781607617433 (hbk. : alk. paper) |
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1607617439 (hbk. : alk. paper) |
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9781607617440 e-ISBN |
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1607617447 e-ISBN |
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