| Description |
1 online resource (xii, 70 pages) : illustrations (chiefly color) |
| Series |
SpringerBriefs in biological imaging |
|
SpringerBriefs in biological imaging.
|
| Contents |
Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology.¡This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists. Table of contetns: Introduction -- Materials & Methods -- Porosome Discovery -- ¡Calcium & SNARE-Induced Membrane Fusion -- SNAREs need to reside in opposing membrane -- Membrane curvature dictates SNARE size -- Disassembly of membrane-associated SNARE complex -- CD spectroscopy confirm membrane requirement for t-/v-SNARE assembly -- SNAREs br ing opposing bilayers closer for calcium bridging -- Membrane lipids influence SNARE complex assembly-disassembly -- Vesicle swelling and content expulsion during cell secretion -- Secretory vesicle swelling is required for intravesicular content expulsion -- Molecular mechanism of secretory vesicle swelling -- Presence of beta receptors at the secretory vesicle membrane -- Conclusion and future studies |
| Summary |
Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology.¡This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
| In |
Springer eBooks |
| Subject |
Cytology.
|
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Ultrastructure (Biology)
|
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Cells -- ultrastructure
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Cells -- metabolism
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Cell Biology
|
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Cytology
|
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ultrastructure.
|
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SCIENCE -- Life Sciences -- Cell Biology.
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Cytology
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Ultrastructure (Biology)
|
| Form |
Electronic book
|
| Author |
Anderson, Lloyd L
|
| ISBN |
9781461424383 |
|
1461424380 |
|
