Title Inflammatory disorders of the nervous system : pathogenesis, immunology, and clinical management / Alireza Minagar, J. Steven Alexander, editors

Edition 2nd ed Published Cham : Humana Press, 2017

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Description 1 online resource (283 pages) Series Current Clinical Neurology Current clinical neurology. Contents 880-01 Emerging Roles of Endothelial Cells in Multiple Sclerosis Pathophysiology and Therapy -- Multiple Sclerosis: Clinical Features, Immunopathogenesis and Treatment -- HIV infection of human nervous system: neurologic manifestations, diagnosis, and treatment -- Central nervous system vasculitis: Immunopathogenesis, clinical aspects, and treatment options -- Neurosarcoidosis: Clinical features, pathogenesis and management -- Cell-derived Microparticles / Exosomes in Neuroinflammation -- Acute disseminated encephalomyelitis: Clinical features, pathophysiology and clinical management -- Autoimmune encephalitis: Clinical features, pathophysiology and treatment -- Neuromyelitis optica: Immunopathogenesis, clinical manifestations, and treatments -- Immunopathogenesis and treatment of Guillain Barre Syndrome and Chronic Inflammatory Demyelinating Polyneuropathy -- Myasthenia gravis: Clinical features, immunology and therapies -- Idiopathic Inflammatory Myopathies -- The venous connection: the role of veins in neurodegenerative disease 880-01/(S Series Editor Introduction; Preface; Contents; List of Contributors; 1: Emerging Roles of€Endothelial Cells in€Multiple Sclerosis Pathophysiology and€Therapy; Introduction; Normal BBB Anatomy and€Physiology; Transport Across the€BBB; Adherens Junctions in€BBB; Tight Junctions in€BBB; Other Junctional Components; Cerebral Endothelial Junctional Disorganization in€MS; Metabolic and€Hypoxic Disturbances of€CNS in€MS; Endothelial Energy Metabolism; Endothelial Microparticles; Endothelial Targets in€MS Therapy; Interferon-β; Chemokines Summary This thoroughly updated edition covers all clinical aspects of neuroinflammation. The latest developments in pathogenesis and advances in treatment are provided, along with an understanding of the immune system's role and interactions between the activated immune cells, cerebral endothelial cells, and other main components of the immune cascade. Cutting-edge and authoritative, this volume offers practitioners a valuable resource for research and clinical practice Notes Cryoglobulinemia-Associated CNS Vasculitis Includes index Bibliography Includes bibliographical references at the end of each chapters and index Notes Print version record Subject Neuritis. Nervous system -- Pathophysiology Inflammation. Inflammation Neuritis Neurology & clinical neurophysiology. HEALTH & FITNESS -- Diseases -- General. MEDICAL -- Clinical Medicine. MEDICAL -- Diseases. MEDICAL -- Evidence-Based Medicine. MEDICAL -- Internal Medicine. Inflammation. Nervous system -- Pathophysiology. Neuritis. Form Electronic book Author Minagar, Alireza. Alexander, J. Steven. ISBN 9783319512204 331951220X 9781499430202 1499430205

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