| Description |
1 online resource (407 pages) : 23 illustrations, 20 illustrations in color |
| Contents |
Chapter 1. Genetics and epigenetics in the neurodegenerative disorders of the central nervous system -- Chapter 2. Diagnosis of Alzheimer's disease typical and atypical forms -- Chapter 3. Genetic complexity of early-onset Alzheimer's disease -- Chapter 4. Genetic risk factors for complex forms of Alzheimer's disease -- Chapter 5. Role of cerebrovascular disease in cognition -- Chapter 6. Risk factors and prevention in Alzheimer's disease and dementia -- Chapter 7. Diagnosis of frontotemporal dementia -- Chapter 8. Autosomal dominant frontotemporal lobar degeneration: from genotype to phenotype -- Chapter 9. Genetic risk factors for sporadic frontotemporal dementia -- Chapter 10. Alzheimer's disease and frontotemporal lobar degeneration: mouse models -- Chapter 11. Fluid biomarkers in Alzheimer's disease and frontotemporal dementia -- Chapter 12. Biomarkers for Alzheimer's disease and frontotemporal lobar degeneration: imaging -- Chapter 13. Genotypic and phenotypic heterogeneity in Amyotrophic lateral sclerosis -- Chapter 14. Lewy body dementia -- Chapter 15. Rare dementias -- Chapter 16. Neurodevelopmental and neurodegenerative alterations in the pathophysiology of schizophrenia: focus on neuro-immuno-inflammation -- Chapter 17. Parkinson's disease: contemporary concepts and clinical management -- Chapter 18. Neurodegeneration and multiple sclerosis |
| Summary |
This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer's disease, frontotemporal lobar degeneration, Lewy body dementia, Parkinson's disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases. Both clinical and basic aspects of each disease are treated, including novel diagnostic criteria, old and new treatments, basic discoveries (genetics, epigenetics and molecular biology), and translation of basic research into biomarkers for early diagnosis, particularly to identify peripheral biomarkers. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (EBSCO, viewed March 22, 2018) |
| Subject |
Nervous system -- Degeneration.
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Neurodegenerative Diseases
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Nerve Degeneration
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Nervous System Physiological Phenomena
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Nervous System -- physiopathology
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Neurosciences.
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Medical genetics.
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Neurology & clinical neurophysiology.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Nervous system -- Degeneration
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| Form |
Electronic book
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| Author |
Galimberti, Daniela, editor
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Scarpini, E. (Elio), editor.
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| ISBN |
9783319729381 |
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3319729381 |
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9783319729398 |
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331972939X |
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9783030102890 |
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3030102890 |
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