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Uniform Title Multiple sclerosis and related disorders (Goodin)
Title Multiple sclerosis and related disorders / series editors, Michael J. Aminoff, François Boller, and Dick F. Swaab ; volume editor, Douglas S. Goodin
Published Edinburgh ; New York : Elsevier, 2014
©2014
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Description 1 online resource (734 pages)
Series Handbook of clinical neurology ; volume 122, 3rd series
Handbook of clinical neurology ; 3rd ser., v. 122. 0072-9752
Contents Immune regulation of multiple sclerosis -- Pathology of multiple sclerosis and related inflammatory demyelinating diseases -- The good and the bad of neuroinflammation in multiple sclerosis -- Demyelination in multiple sclerosis -- Axonal loss in multiple sclerosis: causes and mechanisms -- Insights from magnetic resonance imaging -- Infections and multiple sclerosis -- The experimental autoimmune encephalomyelitis (EAE) model of MS: utility for understanding disease pathophysiology and treatment -- Multiple sclerosis genetics -- Genetics of primary progressive multiple sclerosis -- The epidemiology of multiple sclerosis: insights to disease pathogenesis -- Multiple sclerosis: diagnosis, differential diagnosis and clinical presentation -- MRI mimics of multiple sclerosis -- Diagnosis of multiple sclerosis -- The clinical course of multiple sclerosis -- Early prognosis of multiple sclerosis -- Clinical outcome measures in multiple sclerosis -- MRI outcomes in the diagnosis and disease course of multiple sclerosis -- Multiple sclerosis in children -- Clinical trials in multiple sclerosis -- Glucocorticoid treatment of multiple sclerosis -- Disease-modifying agents in multiple sclerosis -- Immunosuppressive treatments in multiple sclerosis -- Symptomatic treatment and management of multiple sclerosis -- Future treatment approaches to multiple sclerosis -- Neuromyelitis Optica (Devic's syndrome) -- Acute disseminated encephalomyelitis and other inflammatory demyelinating variants -- Acute inflammatory myelopathies -- Clinical neurophysiology of multiple sclerosis -- Cerebrospinal fluid analysis
Summary "Multiple sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners"-- Publisher's description
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Multiple sclerosis.
Multiple sclerosis -- Treatment
Neurology.
Central nervous system -- Diseases -- Periodicals
Multiple sclerosis -- Periodicals
Central nervous system -- Diseases.
Multiple Sclerosis
Neurology
Central Nervous System Diseases
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Central nervous system -- Diseases
Multiple sclerosis
Multiple sclerosis -- Treatment
Neurology
Therapie
Neurologie
Nervensystem
Krankheit
Multiple Sklerose
Nervenentzündung
Genre/Form periodicals.
Periodicals
Periodicals.
Périodiques.
Form Electronic book
Author Goodin, Douglas S
ISBN 0444520015
9780444520012
9780444633095
044463309X
1306424208
9781306424202