| Description |
1 online resource (xiv, 236 pages) : illustrations |
| Contents |
Introduction -- Methods, tools, and resources needed to discover and develop biomarkers -- Guidelines, standards, oversight, and incentives needed for biomarker development -- Methods and process needed for clinical adoption and evaluation of biomarker-based diagnostics |
| Summary |
Many cancer patients are diagnosed at a stage in which the cancer is too far advanced to be cured, and most cancer treatments are effective in only a minority of patients undergoing therapy. Thus, there is tremendous opportunity to improve the outcome for people with cancer by enhancing detection and treatment approaches. Biomarkers will be instrumental in making that transition. Advances in biotechnology and genomics have given scientists new hope that biomarkers can be used to improve cancer screening and detection, to improve the drug development process, and to enhance the effectiveness and safety of cancer care by allowing physicians to tailor treatment for individual patients-an approach known as personalized medicine. However, progress overall has been slow, despite considerable effort and investment, and there are still many challenges and obstacles to overcome before this paradigm shift in oncology can become a reality |
| Bibliography |
Includes bibliographical references |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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English |
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Print version record |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Subject |
Tumor markers.
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Cancer -- Diagnosis.
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Cancer -- Treatment.
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Biochemical markers.
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Biomarkers, Tumor
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Biomarkers
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Neoplasms
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Biochemical markers
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Cancer -- Diagnosis
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Cancer -- Treatment
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Tumor markers
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| Form |
Electronic book
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| Author |
Nass, Sharyl J.
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Moses, Harold L.
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Institute of Medicine (U.S.). Committee on Developing Biomarker-Based Tools for Cancer Screening, Diagnosis, and Treatment.
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| ISBN |
9780309667111 |
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0309667119 |
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0309133998 |
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9780309133999 |
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9786610844333 |
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661084433X |
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