Description |
1 online resource (x, 181 pages) : illustrations |
Contents |
Glycoproteomics in health and disease / Weston B. Struwe, Eoin F.J. Cosgrave, Jennifer C. Byrne, Radka Saldova, and Pauline M. Rudd -- Glyco-engineering of Fc Glycans to enhance the biological functions of therapeutic IgGs / T. Shantha Raju, David M. Knight, and Robert E. Jordan -- Bioinformatics databases and applications available for glycobiology and glycomics / René Ranzinger, Kai Maaß, and Thomas Lütteke -- Lectin microarrays: Simple tools for the analysis of complex glycans / Lakshmi Krishnamoorthy and Lara K. Mahal -- The application of high throughput mass spectrometry to the analysis of glycoproteins / Sasha Singh, Morten Thaysen Andersen, and Judith Jebanathirajah Steen -- Solutions to the glycosylation problem for low- and high-throughput structural glycoproteomics / Simon J. Davis and Max Crispin -- Role of glycoproteins in virus-human cell interactions / Thomas A. Bowden and Elizabeth E. Fry |
Summary |
It has been predicted that nearly half of all human proteins are glycosylated indicating the significance of glycoproteins in human health and disease. For example, the glycans attached to proteins have emerged as important biomarkers in the diagnosis of diseases such as cancers and play a significant role in how pathogenic viruses gain entry into human cells. The study of glycoproteins has now become a truly proteomic science. In the last few years, technology developments including in silico methods, high throughput separation and detection techniques have accelerated the characterization of |
Bibliography |
Includes bibliographical references and index |
Notes |
Print version record |
Subject |
Glycoproteins.
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Proteomics.
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Glycosylation.
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Glycoproteins -- analysis
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Proteomics
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Glycosylation
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SCIENCE -- Life Sciences -- Biochemistry.
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Glycosylation
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Glycoproteins
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Proteomics
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Form |
Electronic book
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Author |
Owens, Raymond J.
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Nettleship, Joanne E. (Joanne Elizabeth)
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ISBN |
9789048193554 |
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9048193559 |
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9789048193547 |
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9048193540 |
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