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Title Neural regeneration / edited by Kwok-Fai So, Xiao-Ming Xu
Published London, UK : Academic Press, 2015

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Description 1 online resource
Contents Front Cover; NEURAL REGENERATION; NEURAL REGENERATION; Copyright; Contents; List of Contributors; SECTION I -- INTRODUCTION; Chapter 1 -- Advances and Challenges for Neural Regeneration Research; 1. NERVOUS SYSTEM, NERVE INJURY, AND NEURAL REGENERATION; 2. TECHNOLOGICAL ADVANCES IN NEURAL REGENERATION RESEARCH; 3. PNS REGENERATION; 4. CNS REGENERATION; 5. CHALLENGES AND OPPORTUNITIES; Acknowledgments; References; SECTION II -- NEURAL REGENERATION INLOWER VERTEBRATES; Chapter 2 -- Functional Regeneration and Remyelination in the Zebrafish Optic Nerve
1. INTRODUCTION TO ZEBRAFISH OPTIC NERVE INJURY (ONI) AS A MODEL FOR STUDYING REGENERATION AND REMYELINATION2. TIME COURSE OF OPTIC NERVE REGENERATION IN ADULT ZEBRAFISH; 3. INTRINSIC AND EXTRINSIC MECHANISMS OF AXON REGENERATION; 4. GENETIC MANIPULATION TOOLS ARE VERY USEFUL FOR STUDYING REGENERATION IN ZEBRAFISH; 5. IN VIVO IMAGING OF NERVE REGENERATION IN ZEBRAFISH LARVAE; 6. IMAGING REMYELINATION IN ZEBRAFISH; 7. BEHAVIOR TESTS INDEXED THE VISUAL FUNCTIONAL RECOVERY AFTER OPTIC NERVE INJURY; 8. FUTURE DIRECTIONS; 9. CONCLUSIONS; Acknowledgments; References
Chapter 3 -- Central Nerve Regeneration in Reptiles1. INTRODUCTION; 2. TIMING OF REGENERATION-GENERAL COMPARED TO FISH AND FROGS, INCLUDING GECKOS, ETC; 3. RETINAL GANGLION CELL SURVIVAL; 4. GLIA: FRIEND OR FOE?; 5. GROWTH PROMOTION: NEUROTROPHINS, EXTRACELLULAR MATRIX, GEFILTIN, POLYSIALIC ACID-NEURAL CELL ADHESION MOLECULE, COMPARISON WI ... ; 6. TOPOGRAPHY AND REFINEMENT: NMDA/AMPA/GABA AND SYNAPTIC PROTEINS; 7. CONCLUSION: RELEVANCE TO MAMMALS; 8. CONCLUSIONS; Acknowledgments; References; Chapter 4 -- Axon Regeneration in the Lamprey Spinal Cord
1. THE NEED FOR LOWER VERTEBRATE MODELS OF AXON REGENERATION IN THE CENTRAL NERVOUS SYSTEM2. GENERAL BIOLOGY OF THE LAMPREY; 3. THE CENTRAL NERVOUS SYSTEM OF THE SEA LAMPREY; 4. ANATOMICAL AND FUNCTIONAL EVIDENCE FOR AXON REGENERATION IN THE LAMPREY SPINAL CORD; 5. IS AXON REGENERATION A RECAPITULATION OF AXON DEVELOPMENT?; 6. NEURON-INTRINSIC DETERMINANTS OF AXON REGENERATION; 7. CONCLUSIONS; References; SECTION III -- NEURAL REGENERATION IN THEPERIPHERAL NERVOUS SYSTEM; Chapter 5 -- Tissue Engineering in Peripheral Nerve Regeneration; 1. INTRODUCTION; 2. NERVE SCAFFOLDS; 3. SUPPORT CELLS
4. GROWTH FACTORS5. CLINICAL APPLICATIONS; 6. CONCLUDING REMARKS; References; Chapter 6 -- Brachial Plexus Avulsion: A Model for Axonal Regeneration Study; 1. ANATOMY OF HUMAN AND RODENT BRACHIAL PLEXUS; 2. BRACHIAL PLEXUS AVULSION; 3. POTENTIAL STRATEGIES FOR THE TREATMENT OF BRACHIAL PLEXUS AVULSION; References; Chapter 7 -- Conditions Affecting Accuracy of Peripheral Nerve Reinnervation and Functional Recovery; 1. THE CLINICAL PROBLEM; 2. PROCESSES FOR AXONAL REGENERATION; 3. FAILURE OF PERIPHERAL NERVE REGENERATION; 4. IMPROVING AXON TARGETING AFTER INJURY; 5. CONCLUSIONS; References
Chapter 8 -- Gonadal Steroids in Regeneration and Repair of Neuromuscular Systems
Summary Annotation Neural Regeneration provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration, including: Neural regeneration in lower vertebratesNeural regeneration in the peripheral nervous systemNeural regeneration in the central nervous systemTransplantation-mediated neural regenerationClinical and translational research on neural regeneration The contributors to this book are experts in their fields and work at distinguished institutions in the United States, Canada, Australia, and China. Nervous system injuries, including peripheral nerve injuries, brain and spinal cord injuries, and stroke affect millions of people worldwide every year. As a result of this high incidence of neurological injuries, neural regeneration and repair is becoming a rapidly growing field dedicated to the new discoveries to promote structural and functional recoveries based on neural regeneration. The ultimate goal is to translate the most optimal regenerative strategies to treatments of human nervous system injuries. This valuable reference book is useful for students, postdoctors, and basic and clinical scientists who are interested in neural regeneration research. Provides an overview of cutting-edge knowledge on a broad spectrum of neural regenerationHighly translational and clinically-relevanceInternational authors who are leaders in their respective fieldsVivid art work making the chapters easily understood
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (ScienceDirect, viewed February 25, 2015)
Subject Nervous system -- Regeneration.
Spinal cord -- Regeneration.
Neural receptors -- Research
Regenerative medicine.
Nerve Regeneration
Regenerative Medicine
Spinal Cord Regeneration
Trauma, Nervous System -- therapy
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Regenerative medicine
Nervous system -- Regeneration
Spinal cord -- Regeneration
Form Electronic book
Author So, Kwok-Fai, editor
Xu, Xiao-Ming, editor
ISBN 9780128018347
0128018348
0128017325
9780128017326