| Description |
1 online resource |
| Contents |
PREFACE ; List of Contributors ; Stem Cells, Developmental Biology and Reparative/ Regenerative Medicine: Tools and Hope for Better Human Life ; The First Morphogenetic Events During Mammalian Development ; INTRODUCTION; 1. MAMMALIAN PRE-IMPLANTATION DEVELOPMENT; Fertilization; Changes in Male Gamete; Changes in Female Gamete; Cleavage; 2. MAMMALIAN DEVELOPMENT DURING IMPLANTATION; 3. EARLY MAMMALIAN POST-IMPLANTATION DEVELOPMENT; Gastrulation; Formation of the Notochord; Establishment of the Body Axes; Changes of the Shape of the Embryonic Disc; Organogenesis; Embryonic Folding |
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Morphogenetic Changes of the Ectodermal Germ LayerMorphogenetic Changes of the Mesodermal Germ Layer; Morphogenetic Changes of the Endodermal Germ Layer; EMBRYONIC STEM CELLS; Introduction ; Embryonic Sources of Stem Cell Lines; Non-Embryonic Sources of Stem Cell Lines; Embryonic Stem Cell Generation and Fate; Clinical Application of Embryonic Stem Cells; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Gene and Signals Regulating Stem Cell Fates ; INTRODUCTION; THE HIERARCHY OF HEMATOPOIETIC CELLS; REGULATION OF HEMATOPOIESIS; CYTOKINES: A KEY REGULATOR OF HSCS |
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FUNCTIONS OF NOTCH PATHWAY IN HSCSFUNCTIONS OF WNT SIGNALING PATHWAY IN THE SELF-RENEWAL OF HSCS; INTERACTION BETWEEN NOTCH AND WNT SIGNAL PATHWAYS IN HSC; FUNCTIONS OF SMAD SIGNALING PATHWAY; FUNCTIONAL ROLES OF ANGIOPOIETIN-LIKE PROTEINS IN HSCS; HSC NICHE; CLINICAL SIGNIFICANCES AND APPLICATIONS OF HSCS IN CELL AND GENE THERAPY; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Stem Cell Biology: Flies As Models and Examples ; BASICS OF STEM CELLS; NICHE REGULATION IN DROSOPHILA GERMLINE STEM CELLS ; STEM CELL NICHE IN THE OVARIAN GERMLINE OF DROSOPHILA |
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STEM CELLS WITHOUT A NICHE: DROSOPHILANEUROBLASTSDEVELOPMENT OF NEUROBLASTS IN DROSOPHILA ; PROGENITOR CELL NICHE IN DROSOPHILA HEMATOPOIETIC PRECURSOR CELLS ; SITES OF TRANSIENT EMBRYONIC HEMATOPOIESIS ; FUNCTIONS OF EXTRACELLULAR MATRIX AND CELL ADHESION PROTEINS IN NICHE MORPHOGENESIS CHARACTERISTICS; DOES IT DIFFER BETWEEN MALE AND FEMALE FLIES? DROSOPHILA; MODE OF DROSOPHILA STEM CELL DIVISION AND REGULATION OF CENTROSOME DYNAMICS; DOES IT DIFFER BETWEEN MALE AND FEMALE FLIES? DROSOPHILA ; MODE OF DROSOPHILA STEM CELL DIVISION AND REGULATION OF CENTROSOME DYNAMICS; CONFLICT OF INTEREST |
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ACKNOWLEDGEMENTSREFERENCES; Behavior and Asymmetric Cell Divisions of Stem Cells ; 1. INTRODUCTION ; 2. SOURCES, BEHAVIOR AND CELLULAR PROPERTIES OF STEM CELLS; 2.1. Stem Cell Sources; 2.2. Behavior and Cellular Properties of Stem Cells: Cell Division, Cell Cycle, and Life Span; 3. SYMMETRIC VERSUS ASYMMETRIC CELL DIVISION; Asymmetry Stem Cell Divisions in Different Systems; Drosophila Intestinal Stem Cells; HEMATOPOIETIC STEM CELLS (HSCS); MUSCLE STEM CELLS; MAMMALIAN EPIDERMAL STEM/PROGENITOR CELLS; MAMMALIAN NEURAL STEM/PROGENITOR CELLS; LUNG EPITHELIAL STEM/PROGENITOR CELLS IN MAMMALS |
| Bibliography |
Includes bibliographical references at the end of each chapters and index |
| Subject |
Stem cells -- Research.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Stem cells -- Research
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| Form |
Electronic book
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| ISBN |
1681082195 |
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9781681082196 |
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