Part I. Impact of the Disease to the Individual and Family -- Chronicity / Pamala D. Larsen -- The illness experience / Pamala D. Larsen -- Psychosocial adjustment / Pamala D. Larsen -- Loss / Pamala D. Larsen -- Spirituality / Rebecca Carron -- Social isolation / Nicholas R. Nicholson, Jr. -- Uncertainty / Faye I. Hummel -- Quality of life / Cheryl Gies -- Adherence / Jill Berg, Robynn Zender, Lorraine S. Evangelista, and Jacqueline M. Dunbar-Jacob -- Family caregiving / Linda L. Pierce and Barbara J. Lutz -- Intimacy / Pamala D. Larsen -- Powerlessness / Faye I. Hummel -- Culture / Susan K. Rice -- Self-management / Raeann LeBlanc and Cynthia Jacelon -- Part II. Impact of the System -- Client and family education / Elaine T. Miller -- Health promotion / Alicia Huckstadt-- The advanced practice nurse in chronic illness care / Ann Marie Hart -- Complementary and alternative therapies / Pamala D. Larsen -- Models of care / Barbara J. Lutz and Pamala D. Larsen -- Home health care / Cynthia S. Jacelon -- Long-term care / Kristen L. Mauk -- Palliative care / Barbara M. Raudonis and Pamala D. Larsen -- Health policy / Anne Deutsch -- Rehabilitation / Kristen L. Mauk